Mesenchymal stem cells

Mesenchymal stem cells give rise to a variety of cell types: bone cells (osteocytes), cartilage cells (chondrocytes), fat cells (adipocytes), and other kinds of connective tissue cells such as those in tendons.

Mesenchymal stem cell based treatment gets clinical approval

May 23, 2012

Health Canada has approved Osiris’ Prochymal, a mesenchymal stem cell treatment, for severe cases of pediatric Graft versus Host Disease (GvHD). Prochymal is a preparation of mesenchymal stem cells, which are obtained from the bone marrow of healthy young adult donors. The stem cells are separated out from the marrow and expanded in culture, so that one donation [...]

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Umbilical Cord Blood MSC Cells Shown to Inhibit Breast Cancer Growth, What Else?

February 7, 2012

Umbilical cord mesenchymal stem cells (MSCs) have been shown to inhibit breast cancer cell growth but it is not known whether this effect is specific to only breast cancer cells. Investigators compared the effects of human Wharton’s jelly stem cell (hWJSC) extracts [conditioned medium (hWJSC-CM) and cell lysate (hWJSC-CL)] on breast adenocarcinoma, ovarian carcinoma and [...]

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What is Wharton’s Jelly?

February 6, 2012

Wharton’s Jelly is a gelatinous substance within the umbilical cord. First named by Thomas Wharton in 1656 this gelatinous substance’s function is to provide support for the vein and arteries of the umbilical cord. During early development of the embryo, perhaps as early as day 3.5 – 7.5E, primitive multipotent stem cells also known as [...]

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Phase 1 Clinical Trial for Multiple Sclerosis Treatment using Stem Cells

October 22, 2011

New Study is the First North American Clinical Trial to Test Adult Mesenchymal Stem Cell Transplantation as a New Therapy for MS A team of researchers at three landmark Cleveland institutions have come together to launch a new clinical trial of an experimental treatment for multiple sclerosis (MS). Researchers at the Cleveland Clinic, University Hospitals [...]

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Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma

October 20, 2011

Abstract Objective: To investigate whether human umbilical cord blood mesenchymal stem cells, a novel source of progenitors with multilineage potential: 1) decrease traumatic brain injury sequelae and restore brain function; 2) are able to survive and home to the lesioned region; and 3) induce relevant changes in the environment in which they are infused. Design: [...]

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Mesenchymal Stem Cells from Umbilical Cord Tissue

August 16, 2011

Mesenchymal stem cells (MSCs) have the capability for renewal and differentiation into various lineages of mesenchymal tissues. These features of MSCs attract a lot of attention from investigators in the context of cell-based therapies of several human diseases. Despite the fact that bone marrow represents the main available source of MSCs, the use of bone [...]

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Study: Umbilical Cord Mesenchymal Stem Cells Infusion for Ulcerative Colitis

August 8, 2011

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cells Infusion for Ulcerative Colitis .  The purpose of this study is to determine whether umbilical cord Mesenchymal Stem Cells of treatment for ulcerative colitis is safe and effective. Ulcerative colitis is characterized as chronic and nonspecific inflammation of gastroenteritis tract．Nowadays etiology and pathogenesis of UC have been unclear．Recent basic research [...]

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What are Adult Stem Cells?

August 6, 2011

An adult stem cell is an undifferentiated cell, found among differentiated cells in a tissue or organ that can renew itself and can differentiate to yield some or all of the major specialized cell types of the particular tissue or organ. The primary roles of adult stem cells are to maintain and repair the tissue [...]

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What are Mesenchymal Stem Cells?

August 6, 2011

The history of research on adult stem cells began over 50 years ago. In the 1950s, researchers discovered that the bone marrow contains at least two kinds of stem cells. One population, called hematopoietic stem cells, forms all the types of blood cells in the body. A second population, called bone marrow stromal stem cells (also called mesenchymal stem [...]

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Study: Umbilical Cord Mesenchymal Stem Cells Infusion in Cirrhosis Patients

July 26, 2011

Umbilical Cord Mesenchymal Stem Cells Infusion Via Hepatic Artery in Cirrhosis Patients.  The purpose of this study is to investigate the efficacy of umbilical cord mesenchymal stem cells (MSCs) infusion via hepatic artery in the treatment of liver cirrhosis. To investigate the efficacy of umbilical cord mesenchymal stem cells (MSCs) infusion via hepatic artery in the treatment of [...]

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