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Stem Cells Offer New Therapeutic Path for Colon Cancer

A promising new approach to treating colorectal cancer involves disarming the gene that drives self-renewal in the stem cells that are the root cause of disease, treatment resistance, and relapse. Colorectal cancer is the third leading cause of cancer-related death in the Western world.

“This is the first step toward clinically applying the principles of cancer stem cell biology to control cancer growth and advance the development of durable cures,” said principal investigator John Dick, PhD, of Princess Margaret Hospital in Toronto, Canada. The findings were published in Nature Medicine (2013; doi:10.1038/nm.3418).


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